Prenatal OPE urinary metabolite blends (ng/mL) and you may CBCL ingredient intense results, using BKMR (Letter = 204)
Mixtures connectivity
Concurrent grows inside density of all the metabolites which have CBCL ingredient intense scores had a low-monotonic, upside-down U-designed trend, having lower CBCL chemical scores on one another highest minimizing quantiles out-of metabolite blends when compared to the median. Although not, as most of the 95% CrI entered 0, there have been no cumulative connections involving the total OPE metabolite mix and internalizing, externalizing, and you will overall dilemmas raw results (discover Fig. 5A, C, and E).
Profile 5 has: 1) the fresh new projected difference between CBCL mixture get when form the metabolites into the percentile specified to the x-axis in contrast to means all of the metabolites on the median philosophy (line 1), 2) this new univariate relationships ranging from for each metabolite and you may CBCL benefit, while you are almost every other metabolites try fixed within their medians, and a carpet area appearing the fresh delivery of your own specified metabolite along side x-axis of each panel (line dos). The patterns have been modified to have recruitment website, maternal years, race/ethnicity, home yearly money, degree, pre-pregnancy Bmi, GA on test range, youngster modified ages at CBCL administration, season, infant delivery purchase, youngster sex.
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